the Isaac boss with Eden. Unlock: Unlock this item by donating 900 coins to the Shop. Has a chance to drop after you beat Krampus. Unlocked by beating each of the Seven Sin mini-bosses once. Enemy projectiles will now slowly curve away from Isaac and avoid hitting him. Any items which are normally a 1 room recharge are now timed instead. Type: Passive Item Pool: Item Room, Angel Room Ghost Baby ItemID: 163 "Spectral buddy" A familiar which follows Isaac and shoots spectral tears that deal.5 damage. Type: Passive, Familiar Item Pool: Item Room Bob's Brain ItemID: 273 "Explosive thoughts" A green brain that launches in the direction you are firing your tears and will explode on contact with enemies, dealing damage and poisoning anything in the blast radius. Bob's Brain deals 60 damage and applies a poison damage over time effect, which will scale with damage upgrades.
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If you also have Lost Contact, tears will bounce off enemy projectiles instead of being destroyed. She can only spawn a maximum of up to 5 spiders at a time and will only do so while there are enemies in the room. Synergizes very well with a lot of items including Tammy's Head, Tiny Planet, Inner Eye (Triple Shot Mutant Spider (Quad Shot) and many others. See the dedicated Devil room page for more details. Unlock: Unlock this item by blowing up 30 slot machines. Tears now revolve around Isaac's Body at a fixed distance until they hit the ground. A fully charged laser deals.5 damage. Type: Passive, Tear Modifier Item Pool: Item Room Pyromaniac Special item ItemID: 223 "Hurts so good 5 bombs" 5 Bombs All explosions now heal Isaac for 1 heart instead of hurting him. Gives you access to the Chest floor. Type: Passive, Familiar Item Pool: Item Room Mystery Sack ItemID: 271 "?" A bag that follows Isaac and drops a random pickup every few rooms (Fixed in patch.04).
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